🩸 Stem cells from one's own body can cure type 1 diabetes

🩸 Stem cells from one's own body can cure type 1 diabetes

A 25-year-old woman with type 1 diabetes began producing her own insulin after stem cell transplantation. The woman has been insulin-free for over a year and can now eat whatever she wants.

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  • A 25-year-old woman with type 1 diabetes began producing her own insulin after stem cell transplantation.
  • The woman has been insulin-free for over a year and can now eat whatever she wants.
  • The study opens up possibilities for a new treatment of diabetes that affects hundreds of millions of people globally.

Groundbreaking treatment with own stem cells

A 25-year-old woman with type 1 diabetes has become the first person to be treated with stem cells from her own body to cure the disease. Less than three months after the transplantation, she began producing her own insulin. Now, more than a year later, she can eat whatever she wants without needing to take insulin.

The woman, who lives in Tianjing, told the journal Nature: "I can eat sugar now. I like to eat everything - especially hotpot."

The study was conducted by researchers at Peking University in Beijing. They extracted cells from three people with type 1 diabetes and reprogrammed them into pluripotent stem cells. These cells were then used to create insulin-producing islets of beta cells.

In June 2023, the equivalent of 1.5 million islets were injected into the woman's abdominal muscles. After two and a half months, she was producing enough insulin to live without extra supplements.

Promising results open new possibilities

James Shapiro, a transplant surgeon and researcher at the University of Alberta, describes the results as astonishing. "They’ve completely reversed diabetes in the patient, who was requiring substantial amounts of insulin beforehand," he says.

Hongkui Deng, a cell biologist at Peking University and one of the study's leaders, says that the results for the other two participants are also "very positive". They will reach the one-year mark in November, after which he hopes to be able to expand the study to an additional 10 or 20 people.

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