💉 New method can reduce diabetes medication dosing to once a month

💉 New method can reduce diabetes medication dosing to once a month

French researchers have developed a system that can reduce the dosing of diabetes medication to once a month. The drug is particularly effective in managing type 2 diabetes and is available in both injectable and oral forms.

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  • French researchers have developed a system that can reduce the dosing of diabetes medication to once a month.
  • The system uses a hydrogel that slowly releases the drug semaglutide over a month.
  • The drug is particularly effective in managing type 2 diabetes and is available in both injectable and oral forms.

Innovative drug administration for diabetes and weight loss

Researchers in France have developed a new system that could change the treatment of type 2 diabetes and obesity. The system is designed to reduce the dosing of the drug semaglutide to just once per month.

Semaglutide, marketed under the names Ozempic, Rybelsus, and Wegovy, is a GLP-1 receptor agonist that helps regulate blood sugar levels and promote weight loss. The drug is particularly effective in managing type 2 diabetes and is available in both injectable and oral forms.

Dr. Claire Mégret from the biotechnology company ADOCIA in Lyon, which developed the hydrogel, explains: "A single injection per month can make it much easier for people with diabetes or obesity to stick to their drug regimens, improve quality of life, and reduce side effects and diabetes complications."

How the hydrogel works

The new delivery system uses a hydrogel formed by two degradable polymers. These polymers are chemically bound to each other to form a gel that allows slow, continuous release of soluble peptides over one to three months.

The researchers found that the hydrogel could be easily injected with a standard needle. The gel began to form within minutes after mixing, ensuring sufficient time for injection while minimizing spread at the injection site.

The next step is to test the hydrogel platform on pigs, whose skin and endocrine systems are most similar to humans. If successful, they will proceed with clinical trials on humans.

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News tips: Thomas Ahlström

❤️ Health Tech📈 Human Progress

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